Is it possible to make a game with python

It is totally possible: www.pygame.org I once started developing a simple 3D labyrinth game in pyglet as a learning project, you might want to take a look: https://www.instagram.com/p/BQ-8ubDDTNi/ https://github.com/kuba-siekierzynski/labyrinth3d

While game developent using Python would not be my first choice. I believe Python has good support for developing games. Here are some engines you may use: https://youtu.be/G7NQF6oCmoo

It is possible.

Yes, but the games would be pretty slow as python is an interpreted language.